ARG70409
Pig BMP4 recombinant protein (His-tagged, C-ter)
Pig BMP4 recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Pig BMP4 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | BMP4 |
| Species | Pig |
| A.A. Sequence | Arg227 - Cys408 |
| Expression System | E. coli |
| Protein Full Name | Bone morphogenetic protein 4 |
| Alternate Names | BMP4; Bone Morphogenetic Protein 4; BMP2B; Bone Morphogenetic Protein 2B; BMP2B1; MCOPS6; BMP-2B; OFC11; BMP-4; ZYME; DVR4 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >98% (by SDS-PAGE) |
| Buffer | 20 mM sodium citrate and 0.2 M NaCl (pH 3.5) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | BMP4 |
|---|---|
| Gene Full Name | Bone Morphogenetic Protein 4 |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. |
| Function | Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis |
| Cellular Localization | Extracellular matrix, Secreted |
| PTM | Cleavage on pair of basic residues, Disulfide bond, Glycoprotein Phosphoprotein |
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ARG70409 Pig Pig BMP4 recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of Pig BMP4 recombinant protein (His-tagged, C-ter)
