ARG30230

Phospho Integrin beta 3 Antibody Panel (Total, pY773, pY785)

Datasheet

Publication1

Ordering Information

Package

Price (USD)

1 kit

669.00

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Component

Cat No	Component Name	Host clonality	Reactivity	Application	Package
ARG51564	anti-CD61 / Integrin beta 3 phospho (Tyr773) antibody	Rabbit pAb	Hu, Ms	IHC-P, WB	50 μl
ARG51763	anti-CD61 / Integrin beta 3 phospho (Tyr785) antibody	Rabbit pAb	Hu, Ms	WB	50 μl
ARG54044	anti-CD61 / Integrin beta 3 antibody (N-term)	Mouse mAb	Hu	WB	50 μl
ARG65350	Goat anti-Mouse IgG antibody (HRP)	Goat pAb	Ms	ELISA, IHC-P, WB	50 μl
ARG65351	Goat anti-Rabbit IgG antibody (HRP)	Goat pAb	Rb	ELISA, IHC-P, WB	50 μl

Overview

Product Description	Cells recognize and respond to their extracellular environment through transmembrane receptors such as integrins, which physically connect the extracellular matrix to the cytoskeleton. Integrins provide the basis for the assembly of intracellular signaling platforms that link to the cytoskeleton and influence nearly every aspect of cell physiology. The integrin beta 3 protein mediates platelet adhesion to immobilized fibrinogen. Adhesion to fibrinogen induced rapid phosphorylation of Integrin beta 3 on Tyr773 and Tyr785 residues, which was reduced by Nitrogen Oxide in a cGMP independent manner. Oberprieler et al. 2007. FEBS Lett 581(7) Legate and Fassler. J Cell Sci 122: 187-98
Target Name	Integrin beta 3
Alternate Names	Phospho Integrin beta 3 antibody; CD61 / Integrin beta 3 phospho (Tyr773) antibody; CD61 / Integrin beta 3 phospho (Tyr785) antibody; CD61 / Integrin beta 3 antibody (N-term)

Properties

Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name	Antibody Panel for Phospho Integrin beta 3 (Total, pY773, pY785)
Research Area	Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody

Images (4) Click the Picture to Zoom In

ARG54044 anti-CD61 / Integrin beta 3 antibody (N-term) WB image

Western blot: 25 µg of Leukocyte lysate stained with ARG54044 anti-CD61 / Integrin beta 3 antibody (N-term) at 1:1000 dilution.
ARG51564 anti-Integrin beta 3 phospho (Tyr773) antibody WB image

Western Blot: extracts from 293 cells stained with anti-Integrin beta 3 (phospho Tyr773) antibody ARG51564 and the same antibody preincubated with blocking peptide.
ARG51564 anti-Integrin beta 3 phospho (Tyr773) antibody IHC-P image

Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-Integrin beta 3 (phospho Tyr773) antibody ARG51564 (left) or the same antibody preincubated with blocking peptide (right).
ARG51763 anti-Integrin beta 3 phospho (Tyr785) antibody WB image

Western Blot: extracts from HUVEC cells stained with anti-Integrin beta 3 (phospho Tyr785) antibody ARG51763 and the same antibody preincubated with blocking peptide .