ARG30198
PAPP A ELISA Antibody Duo
Cell Biology and Cellular Response antibody
Component
Cat No | Component Name | Host clonality | Reactivity | Application | Package |
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ARG10507 | anti-PAPP A antibody [4G11] | Mouse mAb | Hu | ELISA, WB | 500 μg |
ARG10508 | anti-PAPP A antibody [3C8] | Mouse mAb | Hu | ELISA, WB | 500 μg |
Overview
Product Description | PAPP A is a metalloprotease that belongs to the metzincin superfamily of zinc peptidases. The insulin-like growth factor binding protein 4 (IGFBP-4), as well as IGFBP-5 have been found to be specific substrates for PAPP A in vitro. htPAPP A is a widely recognized biochemical marker of Down syndrome (DS) that is used in the first trimester of pregnancy. htPAPP A level in maternal serum increases with gestational age until term. In cases of DS pregnancy, htPAPP A concentration in the first trimester is markedly decreased. Therefore, htPAPP A is currently used as a biochemical marker of DS in the first trimester of pregnancy in combination with free b-subunit of chorionic gonadotropin (bhCG) and nuchal translucency. ARG30198 PAPP A ELISA Duos, includes a capture antibody, ARG10507 PAPP A Protein antibody [4G11] and a detection antibody, ARG10508 PAPP A Protein antibody [3C8], for the quantification of PAPP A expression level by ELISA. |
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Target Name | PAPP A |
Alternate Names | PAPP A ELISA antibody; PAPP A antibody |
Properties
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
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Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Gene Full Name | ELISA Antibody Duo for PAPP A |
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Research Area | Cell Biology and Cellular Response antibody |