ARG30198

PAPP A ELISA Antibody Duo

Cell Biology and Cellular Response antibody

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG10507 anti-PAPP A antibody [4G11] Mouse mAb Hu ELISA, WB 500 μg
ARG10508 anti-PAPP A antibody [3C8] Mouse mAb Hu ELISA, WB 500 μg

Overview

Product Description PAPP A is a metalloprotease that belongs to the metzincin superfamily of zinc peptidases. The insulin-like growth factor binding protein 4 (IGFBP-4), as well as IGFBP-5 have been found to be specific substrates for PAPP A in vitro. htPAPP A is a widely recognized biochemical marker of Down syndrome (DS) that is used in the first trimester of pregnancy. htPAPP A level in maternal serum increases with gestational age until term. In cases of DS pregnancy, htPAPP A concentration in the first trimester is markedly decreased. Therefore, htPAPP A is currently used as a biochemical marker of DS in the first trimester of pregnancy in combination with free b-subunit of chorionic gonadotropin (bhCG) and nuchal translucency. ARG30198 PAPP A ELISA Duos, includes a capture antibody, ARG10507 PAPP A Protein antibody [4G11] and a detection antibody, ARG10508 PAPP A Protein antibody [3C8], for the quantification of PAPP A expression level by ELISA.
Target Name PAPP A
Alternate Names PAPP A ELISA antibody; PAPP A antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name ELISA Antibody Duo for PAPP A
Research Area Cell Biology and Cellular Response antibody