ARG70551
Mouse ZNRF3 recombinant protein (His-tagged)
Mouse ZNRF3 recombinant protein (His-tagged) for SDS-PAGE
Overview
| Product Description | CHO expressed, His-tagged Mouse ZNRF3 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | ZNRF3 |
| A.A. Sequence | Lys53 - Met216 |
| Expression System | CHO |
| Alternate Names | ZNRF3; Zinc And Ring Finger 3; RNF203; BK747E2.3; KIAA1133; RING-Type E3 Ubiquitin Transferase ZNRF3; E3 Ubiquitin-Protein Ligase ZNRF3; Zinc/RING Finger Protein 3; RING Finger Protein 203; FLJ22057; Novel C3HC4 Type Zinc Finger (Ring Finger); CTA-292E10.6; EC 2.3.2.27 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/ml and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | ZNRF3 |
|---|---|
| Gene Full Name | Zinc And Ring Finger 3 |
| Background | Enables frizzled binding activity and ubiquitin-protein transferase activity. Involved in negative regulation of Wnt signaling pathway; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Located in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024] |
| Function | Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification. [Uniprot] |
