ARG70494
Mouse VISTA recombinant protein (His-tagged)
Mouse VISTA recombinant protein (His-tagged) for SDS-PAGE
Overview
| Product Description | CHO expressed, His-tagged Mouse VISTA recombinant protein. |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | VSIR |
| Species | Mouse |
| A.A. Sequence | Met1-Ala191 |
| Expression System | CHO |
| Protein Full Name | V-type immunoglobulin domain-containing suppressor of T-cell activation |
| Alternate Names | VSIR; V-Set Immunoregulatory Receptor; SISP1; VISTA; C10orf54; B7-H5; PD-1H; Dies1; GI24; B7H5; V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation; V-Set Domain-Containing Immunoregulatory Receptor; V-Domain Ig Suppressor Of T Cell Activation; Stress-Induced Secreted Protein-1; PDCD1 Homolog; Sisp-1; Chromosome 10 Open Reading Frame 54; Stress Induced Secreted Protein 1; Platelet Receptor GI24; Platelet Receptor Gi24; Death Domain1alpha; DD1alpha; PP2135 |
Properties
| Form | Powder |
|---|---|
| Purification | >95% (by SDS-PAGE) |
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | VSIR |
|---|---|
| Gene Full Name | V-Set Immunoregulatory Receptor |
| Background | Enables endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of macromolecule metabolic process; and regulation of T cell activation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation. [Uniprot] |
