ARG70494

Mouse VISTA recombinant protein (His-tagged)

Mouse VISTA recombinant protein (His-tagged) for SDS-PAGE

Overview

Product Description CHO expressed, His-tagged Mouse VISTA recombinant protein.
Tested Application SDS-PAGE
Target Name VSIR
Species Mouse
A.A. Sequence Met1-Ala191
Expression System CHO
Protein Full Name V-type immunoglobulin domain-containing suppressor of T-cell activation
Alternate Names VSIR; V-Set Immunoregulatory Receptor; SISP1; VISTA; C10orf54; B7-H5; PD-1H; Dies1; GI24; B7H5; V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation; V-Set Domain-Containing Immunoregulatory Receptor; V-Domain Ig Suppressor Of T Cell Activation; Stress-Induced Secreted Protein-1; PDCD1 Homolog; Sisp-1; Chromosome 10 Open Reading Frame 54; Stress Induced Secreted Protein 1; Platelet Receptor GI24; Platelet Receptor Gi24; Death Domain1alpha; DD1alpha; PP2135

Properties

Form Powder
Purification >95% (by SDS-PAGE)
Purification Note Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test.
Buffer PBS (pH 7.4)
Reconstitution It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
Storage Instruction For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol VSIR
Gene Full Name V-Set Immunoregulatory Receptor
Background Enables endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of macromolecule metabolic process; and regulation of T cell activation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Function May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity).
May stimulate MMP14-mediated MMP2 activation. [Uniprot]