ARG70398
Mouse IL38 recombinant protein (His-tagged, C-ter)
Mouse IL38 recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Mouse IL38 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | IL38 |
| Species | Mouse |
| A.A. Sequence | Met1 - Arg152 |
| Expression System | E. coli |
| Protein Full Name | Interleukin-1 family member 10 |
| Alternate Names | IL1F10; Interleukin 1 Family Member 10; IL-1HY2; IL1-Theta; IL-1F10; FKSG75; Interleukin-1 Receptor Antagonist FKSG75; Interleukin-1 Family Member 10; Family Of Interleukin 1-Theta; Interleukin-1 HY2; Interleukin-38; FIL1 Theta; IL-1 Theta; MGC119832; MGC119833; MGC11983; IL1HY2; IL-38; Interleukin-1 Receptor Antagonist-Like FIL1 Theta; Interleukin 1 Family, Member 10 (Theta); Interleukin 1 Family Member 10 (Theta); IL-1F10 (Canonical Form IL-1F10a); Interleukin-1 Theta; FIL1- Theta; FIL1-Theta; FIL1T; IL38 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >98% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | IL1F10 |
|---|---|
| Gene Full Name | Interleukin 1 Family Member 10 |
| Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. |
| Function | Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2. |
| Cellular Localization | Cytoplasm, Secreted |
Images (1) Click the Picture to Zoom In
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ARG70398 Mouse IL38 recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70398 Mouse IL38 recombinant protein (His-tagged, C-ter)
