ARG70397
Mouse IL31 recombinant protein (His-tagged, C-ter)
Mouse IL31 recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Mouse IL31 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | IL31 |
| Species | Mouse |
| A.A. Sequence | Thr24 - Cys163 |
| Expression System | E. coli |
| Protein Full Name | Interleukin-31 |
| Alternate Names | IL31; Interleukin 31; IL-31; Interleukin-31 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | IL31 |
|---|---|
| Gene Full Name | Interleukin 31 |
| Background | IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. |
| Function | Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. |
| Cellular Localization | Secreted |
| PTM | Glycoprotein |
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ARG70397 Mouse IL31 recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70397 Mouse IL31 recombinant protein (His-tagged, C-ter)
