ARG70397

Mouse IL31 recombinant protein (His-tagged, C-ter)

Mouse IL31 recombinant protein (His-tagged, C-ter) for SDS-PAGE

Overview

Product Description E. coli expressed, His-tagged (C-ter) Mouse IL31 recombinant protein
Tested Application SDS-PAGE
Target Name IL31
Species Mouse
A.A. Sequence Thr24 - Cys163
Expression System E. coli
Protein Full Name Interleukin-31
Alternate Names IL31; Interleukin 31; IL-31; Interleukin-31

Properties

Form Powder
Purification Note Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test.
Purity >95% (by SDS-PAGE)
Buffer PBS (pH 7.4)
Reconstitution It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
Storage Instruction For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol IL31
Gene Full Name Interleukin 31
Background IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma.
Function Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR.
Cellular Localization Secreted
PTM Glycoprotein

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  • ARG70397 Mouse IL31 recombinant protein (His-tagged, C-ter) SDS-PAGE image

    SDS-PAGE analysis of  ARG70397 Mouse IL31 recombinant protein (His-tagged, C-ter)