ARG70395
Mouse IL17B recombinant protein (Active) (His-tagged, C-ter)
Mouse IL17B recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Active Mouse IL17B recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | IL17B |
| Species | Mouse |
| A.A. Sequence | His21 - Phe180 |
| Expression System | E. coli |
| Protein Full Name | Interleukin-17B |
| Activity | Active |
| Activity Note | Determined by its ability to induce IL-8 secretion in HepG2 cells. The ED50 for this effect is <1.5 ng/mL. |
| Alternate Names | IL17B; Interleukin 17B; IL-17B; ZCYTO7; IL-20; NIRF; Neuronal Interleukin-17-Related Factor; Interleukin-17B; MGC138900; MGC138901; Neuronal Interleukin-17 Related Factor; Cytokine-Like Protein ZCYTO7; Interleukin-17 Beta; Cytokine Zcyto7; Interleukin 20; Interleukin-20; IL20 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >98% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | IL17B |
|---|---|
| Gene Full Name | Interleukin 17B |
| Background | The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. |
| Function | Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. |
| Cellular Localization | Secreted |
| PTM | Disulfide bond, Glycoprotein |
Images (1) Click the Picture to Zoom In
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ARG70395 Mouse IL17B recombinant protein (Active) (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70395 Mouse IL17B recombinant protein (Active) (His-tagged, C-ter)
