ARG70394
Mouse IL16 recombinant protein (His-tagged, C-ter)
Mouse IL16 recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Mouse IL16 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | IL16 |
| Species | Mouse |
| A.A. Sequence | His499 - Ser624 |
| Expression System | E. coli |
| Protein Full Name | Pro-interleukin-16 |
| Alternate Names | IL16; Interleukin 16; PrIL-16; LCF; Lymphocyte Chemoattractant Factor; Pro-Interleukin-16; Prointerleukin 16; HsT19289; FLJ42735; FLJ16806; IL-16; Interleukin 16 (Lymphocyte Chemoattractant Factor); Neuronal Interleukin 16; PRIL16; NIL16 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | IL16 |
|---|---|
| Gene Full Name | Interleukin 16 |
| Background | The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. |
| Function | Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. |
| Cellular Localization | Cytoplasm, Nucleus, Secreted |
| PTM | Phosphoprotein |
Images (1) Click the Picture to Zoom In
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ARG70394 Mouse IL16 recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70394 Mouse IL16 recombinant protein (His-tagged, C-ter)
