ARG70540
Mouse Glypican 3 recombinant protein (His-tagged)
Mouse Glypican 3 recombinant protein (His-tagged) for SDS-PAGE
Overview
| Product Description | CHO expressed, His-tagged Mouse Glypican 3 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | Glypican 3 |
| A.A. Sequence | Gln25 - Met557 |
| Expression System | CHO |
| Alternate Names | GPC3; Glypican 3; OCI-5; SGBS1; SGBS; DGSX; SGB; Intestinal Protein OCI-5; Glypican Proteoglycan 3; Glypican-3; GTR2-2; MXR7; SDYS; Heparan Sulphate Proteoglycan; Secreted Glypican-3; OCI5 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/ml and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | GPC3 |
|---|---|
| Gene Full Name | Glypican 3 |
| Background | Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
| Function | Plays a role in regulating cell movements during gastrulation. [Uniprot] |
