ARG83040
Mouse DKK1 ELISA Kit
Mouse DKK1 ELISA Kit for ELISA and Mouse
Overview
| Product Description | ARG83040 Mouse DKK1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse DKK1 in serum, plasma (heparin), ascites, urine and cell culture supernatants. |
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| Tested Reactivity | Ms |
| Tested Application | ELISA |
| Specificity | Not cross-reacts with: Human Dkk4, Kremen1, Kremen2. Mouse Dkk4, Kremen1, Kremen2, LRP6. Rat Dkk4, Kremen1, Kremen2. |
| Target Name | DKK1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Protein Full Name | Dickkopf-related protein 1 |
| Sensitivity | 31.3 pg/ml |
| Sample Type | Serum, plasma (heparin), ascites, urine and cell culture supernatants. |
| Standard Range | 62.5 - 4000 pg/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| Alternate Names | DKK1, Dickkopf WNT Signaling Pathway Inhibitor 1, SK, DKK 1, Dickkopf Related Protein 1, Dickkopf (Xenopus Laevis) Homolog 1, Dickkopf 1 Homolog (Xenopus Laevis), Dickkopf Like Protein 1, Dickkopf 1 Homolog, Dickkopf 1 Like, Dickkopf 1, HDkk 1, Dkk 1 |
Application Instructions
| Assay Time | ~ 4 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | DKK1 |
| Gene Full Name | Dickkopf WNT Signaling Pathway Inhibitor 1 |
| Background | This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017] |
| Function | DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Highlight | Related products: DKK1 antibodies; DKK1 ELISA Kits; |
| PTM | Disulfide bond, Glycoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG83040 Mouse DKK1 ELISA Kit standard curve image
ARG83040 Mouse DKK1 ELISA Kit results of standard run with optical density reading at 450 nm
| Title | Download Link |
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| ARG83040 Mouse DKK1 ELISA Kit User manual |
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