ARG70444
Mouse CXCL16 recombinant protein (Active) (His-tagged, N-ter)
Mouse CXCL16 recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (N-ter) Active Mouse CXCL16 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CXCL16 |
| Species | Mouse |
| A.A. Sequence | Asn27 - Pro114 |
| Expression System | E. coli |
| Protein Full Name | C-X-C Motif Chemokine Ligand 16 |
| Activity | Active |
| Activity Note | Determined by its ability to chemoattract BaF3 cells transfected with mouse CXCR6. The ED50 for this effect is <3 ng/mL. |
| Alternate Names | CXCL16; C X C Motif Chemokine Ligand 16; SR PSOX; SRPSOX; CXCLG16; Scavenger Receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >98% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CXCL16 |
|---|---|
| Gene Full Name | C-X-C Motif Chemokine Ligand 16 |
| Background | Enables chemokine activity. Involved in several processes, including positive regulation of cell growth; response to interferon-gamma; and response to tumor necrosis factor. Located in extracellular space. Biomarker of COVID-19 and systemic scleroderma. |
| Function | Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). |
| Cellular Localization | Cell membrane, Membrane, Secreted |
| PTM | Disulfide bond, Glycoprotein |
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ARG70444 Mouse CXCL16 recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70444 Mouse CXCL16 recombinant protein (Active) (His-tagged, N-ter)
