ARG70493
Mouse CLEC9A recombinant protein (Fc-tagged)
Mouse CLEC9A recombinant protein (Fc-tagged) for SDS-PAGE
Overview
| Product Description | CHO expressed, Fc-tagged Mouse CLEC9A recombinant protein. |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CLEC9A |
| Species | Mouse |
| A.A. Sequence | Lys57-Ile264 |
| Expression System | CHO |
| Protein Full Name | C-type lectin domain family 9 member A |
| Alternate Names | CLEC9A; C-Type Lectin Domain Containing 9A; C-Type Lectin Domain Family 9 Member A; HEEE9341; UNQ9341; DNGR-1; CD370; C-Type Lectin Domain Family 9, Member A; CD370 Antigen; DNGR1 |
Properties
| Form | Powder |
|---|---|
| Purification | >90% (by SDS-PAGE) |
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CLEC9A |
|---|---|
| Gene Full Name | C-Type Lectin Domain Containing 9A |
| Background | CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008] |
| Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. [Uniprot] |
