ARG70502
Mouse CD54 / ICAM1 recombinant protein (His-tagged)
Mouse CD54 / ICAM1 recombinant protein (His-tagged) for SDS-PAGE
Overview
| Product Description | CHO expressed, His-tagged Mouse CD54 / ICAM1 recombinant protein. |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CD54 / ICAM1 |
| Species | Mouse |
| A.A. Sequence | Met1-Asn485 |
| Expression System | CHO |
| Protein Full Name | Intercellular adhesion molecule 1 |
| Alternate Names | ICAM1; Intercellular Adhesion Molecule 1; CD54; BB2; Major Group Rhinovirus Receptor; ICAM-1; Intercellular Adhesion Molecule 1 (CD54), Human Rhinovirus Receptor; Epididymis Secretory Sperm Binding Protein; Cell Surface Glycoprotein P3.58; Human Rhinovirus Receptor; CD54 Antigen; P3.58 |
Properties
| Form | Powder |
|---|---|
| Purification | >95% (by SDS-PAGE) |
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | ICAM1 |
|---|---|
| Gene Full Name | Intercellular Adhesion Molecule 1 |
| Background | his gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008] |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. [Uniprot] |
