ARG70490
Mouse CD36 recombinant protein (His-tagged)
Mouse CD36 recombinant protein (His-tagged) for SDS-PAGE
Overview
| Product Description | CHO expressed, His-tagged Mouse CD36 recombinant protein. |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CD36 |
| Species | Mouse |
| A.A. Sequence | Gly30-Lys439 |
| Expression System | CHO |
| Protein Full Name | Platelet glycoprotein 4 |
| Alternate Names | CD36; CD36 Molecule (CD36 Blood Group); GPIIIB ; GPIV; GP3B; FAT ; GP4; Platelet Glycoprotein 4; Fatty Acid Translocase; SCARB3; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor); CD36 Molecule (Thrombospondin Receptor); Leukocyte Differentiation Antigen CD36; Platelet Glycoprotein IV; Glycoprotein IIIb; PAS IV; Scavenger Receptor Class B, Member 3; Scavenger Receptor Class B Member 3; Platelet Collagen Receptor; Thrombospondin Receptor; Cluster Determinant 36; PAS-4 Protein; CD36 Molecule; CD36 Antigen; BDPLT10; CHDS7; PASIV; PAS-4 |
Properties
| Form | Powder |
|---|---|
| Purification | >95% (by SDS-PAGE) |
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CD36 |
|---|---|
| Gene Full Name | CD36 Molecule (CD36 Blood Group) |
| Background | The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014] |
| Function | Selective and nonredundant sensor of microbial diacylated lipopeptide that signal via TLR2:TLR6 heterodimer, this cluster triggers signaling from the cell surface, leading to the NF-kappa-B-dependent production of TNF, via MYD88 signaling pathway and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. [Uniprot] |
