ARG70405
Mouse CD252 / OX40L recombinant protein (Active) (His-tagged, N-ter)
Mouse CD252 / OX40L recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (N-ter) Active Mouse CD252 / OX40L recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CD252 / OX40L |
| Species | Mouse |
| A.A. Sequence | Gln49 - Leu198 |
| Expression System | E. coli |
| Protein Full Name | Tumor necrosis factor ligand superfamily member 4 |
| Activity | Active |
| Activity Note | Determined by its ability to induce IL-2 secretion in mouse T cells in the presence of the anti-CD3 antibody. The ED50 for this effect is <25 ng/mL. |
| Alternate Names | TNFSF4; TNF Superfamily Member 4; OX-40L; CD252; TXGP1; Tumor Necrosis Factor Ligand Superfamily Member 4; Glycoprotein Gp34; Gp34; Tax-Transcriptionally Activated Glycoprotein 1 (34kD); Tax-Transcriptionally Activated Glycoprotein 1, 34kD; Tumor Necrosis Factor (Ligand) Superfamily, Member 4; Tumor Necrosis Factor (Ligand) Superfamily Member 4; TAX Transcriptionally-Activated Glycoprotein 1; Tumor Necrosis Factor Superfamily Member 4; Tumor Necrosis Factor Ligand 2B; OX40 Antigen Ligand; CD252 Antigen; CD134 Ligand; OX40 Ligand; CD134L; TNLG2B; OX4OL; OX40L; GP34 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | TNFSF4 |
|---|---|
| Gene Full Name | TNF Superfamily Member 4 |
| Background | This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. |
| Function | Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. |
| Cellular Localization | Membrane |
| PTM | Disulfide bond, Glycoprotein |
Images (1) Click the Picture to Zoom In
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ARG70405 Mouse CD252 / OX40L recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70405 Mouse CD252 / OX40L recombinant protein (Active) (His-tagged, N-ter)
