ARG70546

Mouse CD24 recombinant protein (Fc-tagged)

Mouse CD24 recombinant protein (Fc-tagged) for SDS-PAGE

Overview

Product Description HEK293 expressed, Fc-tagged Mouse CD24 recombinant protein
Tested Application SDS-PAGE
Target Name CD24
A.A. Sequence Asn27 - Arg52
Expression System HEK293
Alternate Names CD24; CD24 Molecule; CD24A; CD24 Antigen (Small Cell Lung Carcinoma Cluster 4 Antigen); Signal Transducer CD24; Small Cell Lung Carcinoma Cluster 4 Antigen; CD24 Antigen

Properties

Form Powder
Purification Note Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test.
Purity > 95% (by SDS-PAGE)
Buffer PBS (pH 7.4)
Reconstitution It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/ml and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
Storage Instruction For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol CD24
Gene Full Name CD24 Molecule
Background This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Function In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity. [Uniprot]