ARG70538
Mouse CD223 / LAG3 recombinant protein (His-tagged)
Mouse CD223 / LAG3 recombinant protein (His-tagged) for SDS-PAGE
Overview
| Product Description | HEK293 expressed, His-tagged Mouse CD223 / LAG3 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CD223 / LAG3 |
| A.A. Sequence | Gly 24 - Leu 442 |
| Expression System | HEK293 |
| Alternate Names | LAG3; Lymphocyte Activating 3; CD223; Lymphocyte Activation Gene 3 Protein; Lymphocyte-Activation Gene 3; CD223 Antigen; LAG-3; FDC |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/ml and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | LAG3 |
|---|---|
| Gene Full Name | Lymphocyte Activating 3 |
| Background | Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008] |
| Function | Binds MHC class II (MHC-II); the precise role of MHC-II-binding is however unclear. [Uniprot] |
