ARG80906

Mouse CCL3 / MIP1 alpha ELISA kit

Mouse CCL3 / MIP1 alpha ELISA kit for ELISA and Mouse

Immune System kit

Overview

Product Description ARG80906 Mouse CCL3 / MIP1 alpha ELISA kit is a Enzyme Immunoassay kit for the quantification of Mouse CCL3 / MIP1 alpha in Serum, Plasma, Cell culture supernatants
Tested Reactivity Ms
Tested Application ELISA
Specificity No significant cross-reactivity or interference with MIP-1β, MIP-1γ.
Target Name CCL3 / MIP1 alpha
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm
Sensitivity 1.6 pg/ml
Sample Type Serum, Plasma, Cell culture supernatants
Standard Range 3.125 - 200 pg/ml
Sample Volume 100 µl
Precision CV: less than10%
Alternate Names MIP-1-alpha; SIS-beta; PAT 464.1; Tonsillar lymphocyte LD78 alpha protein; G0/G1 switch regulatory protein 19-1; Small-inducible cytokine A3; C-C motif chemokine 3; LD78-alpha; 4-69; Macrophage inflammatory protein 1-alpha; MIP1A; SCYA3; G0S19-1; LD78ALPHA

Application Instructions

Assay Time 4 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 20302 Mouse CCL3

Swiss-port # P10855 Mouse C-C motif chemokine 3

Gene Symbol Ccl3
Gene Full Name chemokine (C-C motif) ligand 3
Background CCL3 protein also known as macrophage inflammatory protein 1 alpha (MIP-1 alpha), is a small inducible cytokine with inflammatory and chemokinetic properties. It plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. CCL3 is one of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant CCL3 (MIP-1 alpha) induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). [modified from RefSeq 2010 and UniProtKB]
Function Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils. [UniProt]
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CCL3 antibodies; CCL3 ELISA Kits;
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Research Area Immune System kit
PTM N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.

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  • ARG80906 Mouse CCL3 / MIP1 alpha ELISA kit standard curve image

    ARG80906 Mouse CCL3 / MIP1 alpha ELISA kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG80906 Mouse MIP-1 alpha / CCL3 ELISA kit User's manual download icon Download