ARG83485
Mouse C1q / Complement 1q ELISA Kit
Mouse C1q / Complement 1q ELISA Kit for ELISA and Mouse
Overview
| Product Description | ARG83485 Mouse C1q / Complement 1q ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse C1q / Complement 1q in Plasma, Serum |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA |
| Target Name | C1q / Complement 1q |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 1.5 ng/ml |
| Sample Type | Plasma, Serum |
| Standard Range | 3.125 - 200 ng/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| Alternate Names | C1QA; Complement C1q A Chain; Complement Component 1, Q Subcomponent, Alpha Polypeptide; Complement Component 1, Q Subcomponent, A Chain; Complement C1q Subcomponent Subunit A; Complement C1q Chain A; Complement Component C1q, A Chain; C1QD1 |
Application Instructions
| Assay Time | 2 hours |
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Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P98086 Mouse Complement C1q subcomponent subunit A |
|---|---|
| Gene Symbol | C1QA |
| Gene Full Name | complement component 1, q subcomponent, A chain |
| Background | This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants. |
| Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
| Cellular Localization | Secreted |
| PTM | Disulfide bond, Glycoprotein, Hydroxylation |
| Title | Download Link |
|---|---|
| ARG83485 Mouse C1q / Complement 1q ELISA Kit User manual |
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