ARG82665

Monkey IL1RA ELISA Kit

Monkey IL1RA ELISA Kit for ELISA and Monkey

Overview

Product Description ARG82665 Monkey IL1RA ELISA Kit is an Enzyme Immunoassay kit for the quantification of Monkey IL1RA in serum, plasma and cell culture supernatants.
Tested Reactivity Mk
Tested Application ELISA
Target Name IL1RA
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 23.5 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 46.9 - 3000 pg/ml
Sample Volume 100 µl
Precision CV: < 10%
Alternate Names IL1 inhibitor; Interleukin-1 receptor antagonist protein; ICIL-1RA; MVCD4; IL1RA; DIRA; IL-1RN; Anakinra; IL1F3; IRAP; IL-1ra; IL-1ra3

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol IL1RN
Gene Full Name interleukin 1 receptor antagonist
Background The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016]
Function Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. [UniProt]
Cellular Localization Isoform 1: Secreted. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm. Isoform 4: Cytoplasm. [UniProt]
Highlight Related products:
IL1RA antibodies; IL1RA ELISA Kits; IL1RA recombinant proteins;
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  • ARG82665 Monkey IL1RA ELISA Kit standard curve image

    ARG82665 Monkey IL1RA ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG82665 Monkey IL1RA ELISA kit User's manual download icon Download