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ARG30349

MAPK signaling antibody panel

publication_link Publication26

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG51218 anti-SAPK / JNK antibody Rabbit pAb Hu, Ms, Rat IHC-P, WB 20 μl
ARG51807 anti-SAPK / JNK phospho (Thr183 (221) / Tyr185 (223)) antibody Rabbit pAb Hu, Ms, Rat ICC/IF, WB 20 μl
ARG55797 anti-ERK1 + ERK2 antibody Rabbit pAb Hu, Ms, Rat ICC/IF, IHC-P, WB 20 μl
ARG52277 anti-ERK1 + ERK2 phospho (Thr202 / Tyr204) antibody Rabbit pAb Hu, Ms, Rat, Dog ICC/IF, IHC, WB 20 μl
ARG55258 anti-p38 MAPK antibody Rabbit pAb Hu, Ms, Rat ICC/IF, WB 20 μl
ARG51850 anti-p38 MAPK phospho (Thr180 / Tyr182) antibody Rabbit pAb Hu, Ms, Rat WB 20 μl

Overview

Target Name MAPK
Alternate Names MAPK signaling antibody; MAP kinase 9; JNK2BETA; PRKM9; EC 2.7.11.24; c-Jun N-terminal kinase 2; Stress-activated protein kinase 1a; SAPK; Stress-activated protein kinase JNK2; MAPK 9; JNK2; JNK2ALPHA; JNK2A; JNK2B; SAPK1a; JNK-55; Mitogen-activated protein kinase 9; p54a; p54aSAPK; JNK3A; Mitogen-activated protein kinase 10; p54bSAPK; Stress-activated protein kinase 1b; JNK3; c-Jun N-terminal kinase 3; Stress-activated protein kinase JNK3; EC 2.7.11.24; SAPK1b; p493F12; MAP kinase 10; PRKM10; MAPK 10; MAP kinase p49 3F12; CSBP2; PRKM14; MAX-interacting protein 2; SAPK2A; Stress-activated protein kinase 2a; CSBP1; Mxi2; EC 2.7.11.24; CSBP; SAPK2a; RK; CSPB1; MAPK 14; p38; MAP kinase 14; MAP kinase MXI2; Cytokine suppressive anti-inflammatory drug-binding protein; MAP kinase p38 alpha; Mitogen-activated protein kinase p38 alpha; EXIP; CSAID-binding protein; p38ALPHA; PRKM15; Mitogen-activated protein kinase 14 ;MAPK 2; MAPK 1; MAP kinase 2; ERK-2; p41; ERK; MAP kinase 1; PRKM2; PRKM1; EC 2.7.11.24; MAPK2; p40; Extracellular signal-regulated kinase 2; p38; Mitogen-activated protein kinase 2; Mitogen-activated protein kinase 1; ERK2; MAP kinase isoform p42; p42-MAPK; P42MAPK; p41mapk; ERT1

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Images (16) Click the Picture to Zoom In

  • ARG52277 anti-ERK1 + ERK2 phospho (Thr202 / Tyr204) antibody WB image

    Western blot: Madin-Darby Canine Kidney stained with ARG52277 anti-ERK1 + ERK2 phospho (Thr202 / Tyr204) antibody.

    From Heng-Ai Chang et al. Cell Death Discov (2023), doi: 10.1038/s41420-023-01687-5, Fig. S5..

  • ARG51218 nti-SAPK / JNK antibody WB image

    Western blot: Mouse Hippocampus stained with ARG51218 nti-SAPK / JNK antibody.

    From Ya-Shuo Zhao et al. Oxid Med Cell Longev. (2021), doi: 10.1155/2021/8520967, Fig. 6. c.

  • ARG51807 anti-SAPK / JNK phospho (Thr183 (221) / Tyr185 (223)) antibody WB image

    Western blot: 30 µg of HeLa cells untreated or treated with TNF-alpha at 10, 20, or 30 min. The blots were stained with ARG51807 anti-SAPK / JNK phospho (Thr183 (221) / Tyr185 (223)) antibody at 1:500 dilution.

  • ARG55258 anti-p38 MAPK antibody WB image

    Western blot: 30 µg of HeLa treated with TNFa at 0, 10, 20, and 30 min. The blots stained with ARG51850 anti-P38 MAPK phospho (Thr180/Tyr182) antibody, ARG55258 anti-p38 MAPK antibody, and ARG65714 anti-Vinculin antibody.

  • ARG55797 anti-ERK1 + ERK2 antibody WB image

    Western blot: 30 µg of Jurkat, Mouse brain, and Rat brain lysates stained with ARG55797 anti-ERK1 + ERK2 antibody at 1:1000 dilution.

  • ARG51218 anti-SAPK / JNK antibody WB image

    Western blot: Rat Myocardial stained with ARG51218 anti-SAPK / JNK antibody.

    From Ya-Shuo Zhao et al. Oxidative Medicine and Cellular Longevity. (2019), doi: 10.1155/2019/7415212, Fig. 4. d.

  • ARG51807 anti-SAPK / JNK phospho (Thr183 (221) / Tyr185 (223)) antibody WB image

    Western blot: Extracts from C6 cells untreated or treated with anisomycin. The blots were stained with ARG51807 anti-SAPK / JNK phospho (Thr183 (221) / Tyr185 (223)) antibody.

  • ARG52277 anti-ERK1 + ERK2 phospho (Thr202 / Tyr204) antibody WB image

    Western blot: 30 µg of HeLa cells untreated or treated with TNF-alpha at 20 ng/ml dilution (10, 20, and 30 min). The blots were stained with ARG52277 anti-ERK1 + ERK2 phospho (Thr202 / Tyr204) antibody at 1:1000 dilution.

  • ARG51218 anti-SAPK / JNK antibody WB image

    Western blot: 30 µg of HeLa cells untreated or treated with TNF-alpha at 20 ng/ml dilution (10, 20, and 30 min). The blots were stained with ARG51218 anti-SAPK / JNK antibody at 1:500 dilution.

  • ARG51807 anti-SAPK / JNK phospho (Thr183 (221) / Tyr185 (223)) antibody ICC/IF image

    Immunofluorescence: Methanol-fixed HeLa cells stained with ARG51807 anti-SAPK / JNK phospho (Thr183 (221) / Tyr185 (223)) antibody.

  • ARG55258 anti-p38 MAPK antibody ICC/IF image

    Immunofluorescence: A549 cell stained with ARG55258 anti-p38 MAPK antibody. Blue: DAPI for nuclear staining.

  • ARG51218 anti-SAPK / JNK antibody IHC-P image

    Immunohistochemistry: paraffin-embedded Human breast carcinoma tissue stained with ARG51218 anti-SAPK / JNK antibody (left) or the same antibody preincubated with blocking peptide (right).

  • ARG55258 anti-p38 MAPK antibody WB image

    Western blot: 30 µg of HeLa, and Mouse liver lysate stained with ARG55258 anti-p38 MAPK antibody at 1:2000 dilution.

  • ARG55797 anti-ERK1 + ERK2 antibody WB image

    Western blot: 30 µg of Rat spleen lysate stained with ARG55797 anti-ERK1 + ERK2 antibody at 1:500 dilution.

  • ARG55797 anti-ERK1 + ERK2 antibody WB image

    Western blot: 30 µg of 1) HeLa, 2) HeLa + EGF 5 min, and 3) HeLa + EGF 10 min stained with ARG52277 anti-ERK1 + ERK2 phospho (Thr202 / Tyr204) antibody (Top) and ARG55797 anti-ERK1 + ERK2 antibody (Bottom) at 1:1000 dilution.

  • ARG51807 anti-SAPK / JNK phospho (Thr183 (221) / Tyr185 (223)) antibody WB image

    Western blot: Extracts from 293 cells, treated with Anisomycin or calf intestinal phosphatase (CIP). The blots were stained with ARG51807 anti-SAPK / JNK phospho (Thr183 (221) / Tyr185 (223)) antibody.

Specific References

HuMSC-EVs Protect Endothelial Cells Against Hypoxia/Reoxygenation Injury by Inhibiting the Pannexin 1/p38-MAPK Pathway

ARG51850: WB / Human

Qian Ma et al.
Transplantation Proceedings,  (2024)

publication_link

 

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Shionone relieves oxygen-glucose deprivation/reoxygenation induced SH-SY5Y cells injury by inhibiting the p38 MAPK/NF-κB pathway

ARG51850: WB / Human

Xiaoli Zhou et al.
J Cardiothorac Surg,  (2024)

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Caveolin-1 differentially regulates the transforming growth factor-β and epidermal growth factor signaling pathways in MDCK cells

ARG52277: WB / Dog

Shih-Chuan Hsiao et al.
Biochim Biophys Acta Gen Subj.,  (2024)

publication_link

 

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Structural characterization and immunomodulatory activity of an acidic polysaccharide from walnut green husk

ARG51850: WB / Mouse

Guoliang Wang et al.
Journal of Functional Foods,  (2023)

publication_link

 

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YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions

ARG52277: WB / Dog

Heng-Ai Chang et al.
Cell Death Discov.,  (2023)

publication_link

 

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DHPA Protects SH-SY5Y Cells from Oxidative Stress-Induced Apoptosis via Mitochondria Apoptosis and the Keap1/Nrf2/HO-1 Signaling Pathway

ARG51850: WB / Human

Yunhui Cai  et al.
Antioxidants (Basel),  (2022)

publication_link

 

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Kaempferol-Driven Inhibition of Listeriolysin O Pore Formation and Inflammation Suppresses Listeria monocytogenes Infection

ARG51807: WB / Mouse

Tingting Wang et al.
Microbiol Spectr.,  (2022)

publication_link

 

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Cobalt protoporphyrin promotes human keratinocyte migration under hyperglycemic conditions

ARG51850, ARG55258: WB / Human

Peng-Hsiang Fang et al.
Molecular Medicine,  (2022)

publication_link

 

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Angiotensin II Induces Cardiac Edema and Hypertrophic Remodeling through Lymphatic-Dependent Mechanisms

ARG51850, ARG55258: WB / Mouse

Jie Bai et al.
Oxid Med Cell Longev.,  (2022)

publication_link

 

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Shikonin Induced Program Cell Death through Generation of Reactive Oxygen Species in Renal Cancer Cells

ARG51850, ARG52277: WB / Human

Ming-Feng Tsai et al.
Antioxidants (Basel).,  (2021)

publication_link

 

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Involvement of Hepcidin in Cognitive Damage Induced by Chronic Intermittent Hypoxia in Mice.

ARG51218: WB / Mouse

Ya-Shuo Zhao et al.
Oxid Med Cell Longev.,  (2021)

publication_link

 

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Simvastatin Enhances the Chondrogenesis But Not the Osteogenesis of Adipose-Derived Stem Cells in a Hyaluronan Microenvironment.

ARG51807, ARG51218: WB / Human

Shun-Cheng Wu et al.
Biomedicines.,  (2021)

publication_link

 

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Angiotensin-(1-7) treatment blocks lipopolysaccharide-induced organ damage, platelet dysfunction, and IL-6 and nitric oxide production in rats.

ARG51850: WB / Rat

Hsin-Jung Tsai et al.
Sci Rep.,  (2021)

publication_link

 

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Inhibition of inflammatory response by α-lipoic acid in autoimmune thyroiditis mice.

ARG55258: WB / Mouse

Mayinu Yusufu et al.
Basic & Clinical Medicine.,  (2021)

publication_link

 

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Polyphenols from Toona sinensiss Seeds Alleviate Neuroinflammation Induced by 6-Hydroxydopamine Through Suppressing p38 MAPK Signaling Pathway in a Rat Model of Parkinson's Disease.

ARG55258: WB, ICC-IF / Rat

Zhuang Wenxin et al.
Neurochem Res.,  (2020)

publication_link

 

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Lipocalin2 promotes cell proliferation and migration in ovarian cancer through activation of the ERK/GSK3β/β-catenin signaling pathway.

ARG52277, ARG55797: WB / Human

Peipei Hao et al.
Life Sci.,  (2020)

publication_link

 

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Discoidin Domain Receptor 1 Regulates Runx2 during Osteogenesis of Osteoblasts and Promotes Bone Ossification via Phosphorylation of p38.

ARG55258: WB / Mouse

Liang-Yin Chou et al.
Int J Mol Sci.,  (2020)

publication_link

 

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A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection.

ARG52277, ARG51807: WB / Mouse

Tingting Wang et al.
Front Cell Infect Microbiol.,  (2020)

publication_link

 

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The Different Effects of IFN- β and IFN- γ on the Tumor-Suppressive Activity of Human Amniotic Fluid-Derived Mesenchymal Stem Cells

ARG51850, ARG51807: WB / Human

Jingchun Du et al.
Stem Cells Int.,  (2019)

publication_link

 

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Interplay between Redox Signaling, Oxidative Stress, and Unfolded Protein Response (UPR) in Pathogenesis of Human Diseases.

ARG51218: WB / Rat

Poplawski Tomasz et al.
Oxid Med Cell Longev.,  (2019)

publication_link

 

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The fucoidan from sea cucumber Apostichopus japonicus attenuates lipopolysaccharide-challenged liver injury in C57BL/6J mice.

ARG51807: WB / Mouse

Yin Jiayu et al.
Journal of Functional Foods.,  (2019)

publication_link

 

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Hydrogen protects against chronic intermittent hypoxia induced renal dysfunction by promoting autophagy and alleviating apoptosis.

ARG51218: WB / Rat

Guan Peng et al.
Life Sci.,  (2019)

publication_link

 

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Hydrogen and Oxygen Mixture to Improve Cardiac Dysfunction and Myocardial Pathological Changes Induced by Intermittent Hypoxia in Rats.

ARG51218: WB / Rat

Zhao Ya-Shuo et al.
Oxidative Medicine and Cellular Longevity.,  (2019)

publication_link

 

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Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury.

ARG51807: WB / Mouse

Homma Takujiro et al.
Toxicol Lett.,  (2018)

publication_link

 

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Four new antitumor metabolites isolated from a mutant 3-f-31 strain derived from Penicillium purpurogenum G59.

ARG52277, ARG55797: WB / Human

Wang Nan et al.
Eur J Med Chem.,  (2018)

publication_link

 

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Indirubin Inhibits LPS-Induced Inflammation via TLR4 Abrogation Mediated by the NF-kB and MAPK Signaling Pathways.

ARG55258, ARG51218: WB / Mouse

Lai JL et al.
Inflammation.,  (2016)

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