In the female menstrual cycle, during a 24-48 hour period, luteinizing hormone (LH) is rapidly released from gonadotropic cells in pituitary gland as a result of positive feedback regulation by the elevated estrogen during follicle maturation. The LH surge triggers the release of mature egg from ovarian follicle and the development of remaining follicle into corpus luteum. Progesterone secreted by corpus luteum is needed for preparing the endometrium for egg implantation. LH is critical for ovulation in women. In men, LH stimulates testis to produce testosterone.

LH has an α subunit that is identical to the one in other glycoprotein hormones such as TSH, FSH and HCG. LH level is used for predicating ovulation in women to increase the chance of insemination.

ARG30058 Luteinizing Hormone ELISA Duos, includes a capture antibody, ARG10177 LH antibody [LH-1] and a HRP-conjugated tracer antibody, ARG10178 LH antibody [LH-2] (HRP), for studying the luteinizing hormone (LH) protein expression level by ELISA.