ARG83441
Human beta Catenin ELISA Kit
Human beta Catenin ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83441 Human beta Catenin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human beta Catenin in Serum, plasma and cell culture supernatants., Tissue Homogenates |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | beta Catenin |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 6.4 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatants., Tissue Homogenates |
| Standard Range | 15.6 - 1000 pg/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | CTNNB; armadillo; MRD19; Catenin beta-1; Beta-catenin |
Application Instructions
| Assay Time | 3.5 hours |
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Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CTNNB1 |
| Gene Full Name | Catenin Beta 1 |
| Background | Catenin is one of the key downstream effectors in the Wnt signaling pathway. It has been implicated to play an important role in early embryonic development and tumorigenesis. β-catenin can be destabilized by GSK-3β or other kinases by phosphorylating it at serines 33, 37, 45 and threonine 41. Mutations of these phosphorylation sites in β-catenin have been found in many tumor cell lines. |
| Function | Key downstream component of the canonical Wnt signaling pathway |
| Cellular Localization | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Nucleus, Synapse |
| Highlight | Related products: beta Catenin antibodies; beta Catenin Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: Besides tumor suppression, what’s p53 busy for during embryogenesis? Wnt / beta-catenin signaling for gastric fundus specification |
| PTM | Acetylation, Glycoprotein, Phosphoprotein, S-nitrosylation, Ubl conjugation |
Images (1) Click the Picture to Zoom In
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ARG83441 Human beta Catenin ELISA Kit standard curve image
ARG83441 Human beta Catenin ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83441 Human beta Catenin ELISA Kit User manual |
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