ARG82922

Human alpha 2 Antiplasmin ELISA Kit

Human alpha 2 Antiplasmin ELISA Kit for ELISA and Human

Cell Biology and Cellular Response antibody; Neuroscience antibody

Overview

Product Description ARG82922 Human alpha 2 Antiplasmin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human alpha 2 Antiplasmin in Serum, Plasma (heparin, EDTA, citrate), Cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity There is no detectable cross-reactivity with other relevant proteins.
Target Name alpha 2 Antiplasmin
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 15 pg/ml
Detection Range 1.56 ng/ml - 100 ng/ml
Sample Type Serum, Plasma and Cell culture supernatants.
Precision Intra-Assay CV: 5.5%
Inter-Assay CV: 7.2%
Alternate Names Alpha-2-AP; Serpin F2; Alpha-2-PI; Alpha-2-antiplasmin; Alpha-2-plasmin inhibitor; AAP; API; PLI; A2AP; ALPHA-2-P

Application Instructions

Assay Time ~ 5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5345 Human SERPINF2

Swiss-port # P08697 Human Alpha-2-antiplasmin

Gene Symbol SERPINF2
Gene Full Name serpin family F member 2
Background This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Function Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
Cellular Localization Secreted.
Research Area Cell Biology and Cellular Response antibody; Neuroscience antibody
PTM Proteolytically cleaved at Pro-39 by both the prolyl endopeptidase FAP form and antiplasmin-cleaving enzyme FAP soluble form to generate mature alpha-2-antiplasmin.

Images (1) Click the Picture to Zoom In

  • ARG82922 Human alpha 2 Antiplasmin ELISA Kit standard curve image

    ARG82922 Human alpha 2 Antiplasmin ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG82922 Human alpha 2 Antiplasmin ELISA Kit User manual download icon Download