ARG82367
Human Transthyretin / Prealbumin ELISA Kit
Human Transthyretin / Prealbumin ELISA Kit for ELISA and Human
Component
| Cat No | Component Name | Package | Temp |
|---|---|---|---|
| ARG82367-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG82367-002 | Standard | 2 X 10 ng/vial | 4°C |
| ARG82367-003 | Standard/Sample diluent | 30 ml (Ready to use) | 4°C |
| ARG82367-004 | Antibody conjugate concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG82367-005 | Antibody diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG82367-006 | HRP-Streptavidin concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG82367-007 | HRP-Streptavidin diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG82367-008 | 25X Wash buffer | 20 ml | 4°C |
| ARG82367-009 | TMB substrate | 10 ml (Ready to use) | 4°C (Protect from light) |
| ARG82367-010 | STOP solution | 10 ml (Ready to use) | 4°C |
| ARG82367-011 | Plate sealer | 4 strips | Room temperature |
Overview
| Product Description | ARG82367 Human Transthyretin / Prealbumin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Transthyretin / Prealbumin in serum, plasma (EDTA, heparin) and cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | Transthyretin / Prealbumin |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 156 pg/ml |
| Sample Type | Serum, plasma (EDTA, heparin) and cell culture supernatants. |
| Standard Range | 312 - 20000 pg/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: 5.3% Inter-Assay CV: 7.2% |
| Alternate Names | TBPA; HEL111; ATTR; CTS; Transthyretin; CTS1; PALB; HsT2651; Prealbumin |
Application Instructions
| Assay Time | ~ 5 hours |
|---|
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TTR |
| Gene Full Name | transthyretin |
| Background | This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009] |
| Function | Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. [UniProt] |
| Cellular Localization | Secreted. Cytoplasm. [UniProt] |
| Highlight | Related products: Transthyretin antibodies; Transthyretin ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| PTM | Not glycosylated under normal conditions. Following unfolding, caused for example by variant AMYL-TTR 'Gly-38', the cryptic Asn-118 site is exposed and glycosylated by STT3B-containing OST complex, leading to its degradation by the ER-associated degradation (ERAD) pathway. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG82367 Human Transthyretin / Prealbumin ELISA Kit standard curve image
ARG82367 Human Transthyretin / Prealbumin ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG82367 Human Transthyretin / Prealbumin ELISA Kit User manual |
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