ARG81190
Human SERPINF1 / PEDF ELISA Kit
Human SERPINF1 / PEDF ELISA Kit for ELISA and Human
Overview
| Product Description | ARG81190 Human SERPINF1 / PEDF ELISA is an Enzyme Immunoassay kit for the quantification of Human PEDF in serum, plasma or cell culture media |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | SERPINF1 / PEDF |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm |
| Detection Range | Linear Range: 2.2 - 140 ng/ml |
| Sample Type | Serum, plasma or cell culture media |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 15% |
| Alternate Names | OI6; OI12; PEDF; EPC-1; PIG35; Serpin F1; pigment epithelium-derived factor |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SERPINF1 |
| Gene Full Name | serpin family F member 1 |
| Background | This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016] |
| Function | Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. [UniProt] |
| Highlight | Related products: Serpin antibodies; Serpin ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| PTM | The N-terminus is blocked. Extracellular phosphorylation enhances antiangiogenic activity. N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. |
Images (1) Click the Picture to Zoom In
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ARG81190 Human SERPINF1 / PEDF ELISA Kit standard curve image
ARG81190 Human SERPINF1 / PEDF ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG81190 Human SERPINF1-PEDF ELISA Kit User manual |
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