ARG81037
Human Protein C ELISA Kit
Human Protein C ELISA Kit for ELISA and Human
Cell Biology and Cellular Response kit
Overview
| Product Description | ARG81037 Human Protein C ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Protein C in plasma (citrate). |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | Protein C |
| Conjugation | HRP |
| Conjugation Note | TMB at 450 nm |
| Sensitivity | 0.06 |
| Sample Type | Plasma (citrate). |
| Standard Range | 12.5 - 150 % |
| Sample Volume | 20 µl |
| Alternate Names | EC 3.4.21.69; Blood coagulation factor XIV; PC; THPH3; Vitamin K-dependent protein C; THPH4; APC; Autoprothrombin IIA; PROC1; Anticoagulant protein C |
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PROC |
| Gene Full Name | protein C (inactivator of coagulation factors Va and VIIIa) |
| Background | This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009] |
| Function | Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. [UniProt] |
| Highlight | Related products: Protein C antibodies; Protein C ELISA Kits; Protein C Duos / Panels; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Research Area | Cell Biology and Cellular Response kit |
| PTM | The vitamin K-dependent, enzymatic carboxylation of some Glu residues allows the modified protein to bind calcium. N- and O-glycosylated. Partial (70%) N-glycosylation of Asn-371 with an atypical N-X-C site produces a higher molecular weight form referred to as alpha. The lower molecular weight form, not N-glycosylated at Asn-371, is beta. O-glycosylated with core 1 or possibly core 8 glycans. The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. May be phosphorylated on a Ser or Thr in a region (AA 25-30) of the propeptide. |
Images (1) Click the Picture to Zoom In
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ARG81037 Human Protein C ELISA Kit standard curve image
ARG81037 Human Protein C ELISA Kit results of a typical standard run with optical density reading at 450 / 620 nm.
| Title | Download Link |
|---|---|
| ARG81037 Human Protein C ELISA Kit User's manual |
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