ARG83041
Human Pro-Collagen I alpha 1 ELISA Kit
Human Pro-Collagen I alpha 1 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83041 Human Pro-Collagen I alpha 1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Pro-Collagen I alpha 1 in serum, plasma (heparin), ascites, urine and cell culture supernatants. |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | Not cross-reacts with: Human BMP2, BMP4, TIE2, Collagen II, Collagen III alpha1. Mouse BCMA, VEGF, TNF alpha, Collagen II. Rat Collagen II |
| Target Name | Pro-Collagen I |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Protein Full Name | Collagen alpha-1(I) chain |
| Sensitivity | 31.25 pg/ml |
| Sample Type | Serum, plasma (heparin), ascites, urine and cell culture supernatants. |
| Standard Range | 62.5 - 4000 pg/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| Alternate Names | COL1A1, Collagen Type I Alpha 1 Chain, OI4, Collagen, Type I, Alpha 1, Collagen Alpha-1(I) Chain, Alpha-1 Type I Collagen, Collagen Of Skin, Tendon And Bone, Alpha-1 Chain, Collagen Alpha-1(I) Chain Preproprotein, Type I Procollagen Alpha 1 Chain, Collagen Alpha 1 Chain Type I, Pro-Alpha-1 Collagen Type , Alpha1(I) Procollagen, Type I Proalpha, EDSARTH1, CAFYD, EDSC, OI1, OI2, OI3 |
Application Instructions
| Assay Time | ~ 4 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
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| Gene Symbol | COL1A1 |
| Gene Full Name | Collagen Type I Alpha 1 Chain |
| Background | This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008] |
| Function | Type I collagen is a member of group I collagen (fibrillar forming collagen). [UniProt] |
| Cellular Localization | Extracellular matrix, Secreted. [UniProt] |
| Highlight | Related products: Collagen I antibodies; Collagen I ELISA Kits; Collagen I Duos / Panels |
| PTM | Disulfide bond, Glycoprotein, Hydroxylation, Phosphoprotein, Pyrrolidone carboxylic acid. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG83041 Human Pro-Collagen I alpha 1 ELISA Kit curve image
ARG83041 Human Pro-Collagen I alpha 1 ELISA Kit run with optical density reading at 450 nm
| Title | Download Link |
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| ARG83041 Human Pro-Collagen I alpha 1 ELISA Kit User manual |
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