ARG70453
Human PGA5 recombinant protein (His-tagged, C-ter)
Human PGA5 recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Human PGA5 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | PGA5 |
| Species | Human |
| A.A. Sequence | Met1 - Ala388 |
| Expression System | E. coli |
| Protein Full Name | Pepsin A-5 |
| Alternate Names | PGA5; Pepsinogen A5; Pepsinogen 5, Group I (Pepsinogen A); Pepsinogen-5; Pepsin A-5; Pepsin A; Pepsinogen-4 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >95% (by SDS-PAGE) |
| Buffer | PBS (pH 8.0) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | PGA5 |
|---|---|
| Gene Full Name | Pepsinogen A5 |
| Background | This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. |
| Function | Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. |
| Cellular Localization | Secreted |
| PTM | Disulfide bond, Phosphoprotein, Zymogen |
Images (1) Click the Picture to Zoom In
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ARG70453 Human PGA5 recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70453 Human PGA5 recombinant protein (His-tagged, C-ter)
