ARG83670

Human / Mouse COX2 ELISA Kit

Human / Mouse COX2 ELISA Kit for ELISA and Human,Mouse

Overview

Product Description ARG83670 Human / Mouse COX2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human, Mouse COX2 in Cell lysates.
Tested Reactivity Hu, Ms
Tested Application ELISA
Target Name COX2
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 50 pg/ml
Sample Type Cell lysates.
Standard Range 156 - 10000 pg/ml
Sample Volume 100 μl
Precision Intra-Assay CV: < 10%
Inter-Assay CV: < 10%
Alternate Names PTGS2; Prostaglandin-Endoperoxide Synthase 2; COX2; Prostaglandin G/H Synthase 2; Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase And Cyclooxygenase); Prostaglandin H2 Synthase 2; Cyclooxygenase 2; PGH Synthase 2; EC 1.14.99.1; PGHS-2; PHS II; COX-2; Cyclooxygenase 2b; Cyclooxygenase-2; EC 1.14.99; GRIPGHS; PGG/HS; HCox-2; PHS-2

Application Instructions

Assay Time 4 hours

Properties

Form 96 well
Storage Instruction Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 19225 Mouse PTGS2

GeneID: 5743 Human PTGS2

Swiss-port # P35354 Human Prostaglandin G/H synthase 2

Swiss-port # Q05769 Mouse Prostaglandin G/H synthase 2

Gene Symbol PTGS2
Gene Full Name Prostaglandin-Endoperoxide Synthase 2
Background Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Function During neuroinflammation, plays a role in neuronal secretion of specialized preresolving mediators (SPMs) 15R-lipoxin A4 that regulates phagocytic microglia. [Uniprot]
Cellular Localization Endoplasmic reticulum, Membrane, Microsome, Nucleus. [Uniprot]
PTM Acetylation, Disulfide bond, Glycoprotein, S-nitrosylation. [Uniprot]

Images (1) Click the Picture to Zoom In

  • ARG83670 Human / Mouse COX2 ELISA Kit standard curve image

    ARG83670 Human / Mouse COX2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG83670 Human / Mouse COX2 ELISA Kit User manual download icon Download