ARG83670
Human / Mouse COX2 ELISA Kit
Human / Mouse COX2 ELISA Kit for ELISA and Human,Mouse
Overview
Product Description | ARG83670 Human / Mouse COX2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human, Mouse COX2 in Cell lysates. |
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Tested Reactivity | Hu, Ms |
Tested Application | ELISA |
Target Name | COX2 |
Conjugation | HRP |
Conjugation Note | Substrate: TMB and read at 450 nm. |
Sensitivity | 50 pg/ml |
Sample Type | Cell lysates. |
Standard Range | 156 - 10000 pg/ml |
Sample Volume | 100 μl |
Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
Alternate Names | PTGS2; Prostaglandin-Endoperoxide Synthase 2; COX2; Prostaglandin G/H Synthase 2; Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase And Cyclooxygenase); Prostaglandin H2 Synthase 2; Cyclooxygenase 2; PGH Synthase 2; EC 1.14.99.1; PGHS-2; PHS II; COX-2; Cyclooxygenase 2b; Cyclooxygenase-2; EC 1.14.99; GRIPGHS; PGG/HS; HCox-2; PHS-2 |
Application Instructions
Assay Time | 4 hours |
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Properties
Form | 96 well |
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Storage Instruction | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | PTGS2 |
Gene Full Name | Prostaglandin-Endoperoxide Synthase 2 |
Background | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009] |
Function | During neuroinflammation, plays a role in neuronal secretion of specialized preresolving mediators (SPMs) 15R-lipoxin A4 that regulates phagocytic microglia. [Uniprot] |
Cellular Localization | Endoplasmic reticulum, Membrane, Microsome, Nucleus. [Uniprot] |
PTM | Acetylation, Disulfide bond, Glycoprotein, S-nitrosylation. [Uniprot] |
Images (1) Click the Picture to Zoom In
Title | Download Link |
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ARG83670 Human / Mouse COX2 ELISA Kit User manual |
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