Overview

Product Description	ARG80643 Human MUC16 / CA125 ELISA Kit is an enzyme immunoassay kit for the quantification of MUC16 / CA125 in serum and plasma (EDTA, heparin, citrate).
Tested Reactivity	Hu
Tested Application	ELISA
Target Name	MUC16 / CA125
Sensitivity	0.25 U/ml
Sample Type	Serum and plasma (EDTA, heparin, citrate).
Standard Range	55 - 600 U/ml
Sample Volume	50 µl
Alternate Names	Mucin-16; MUC-16; Ovarian carcinoma antigen CA125; CA125; Ovarian cancer-related tumor marker CA125; CA-125

Application Instructions

Assay Time	60, 15 min

Properties

Form	96 well
Storage Instruction	Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 94025 Human MUC16 Swiss-port # Q8WXI7 Human Mucin-16
Gene Symbol	MUC16
Gene Full Name	mucin 16, cell surface associated
Function	Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. [UniProt]
Highlight	Related products: MUC16 antibodies; MUC16 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData
Research Area	Cancer kit; Controls and Markers kit; Signaling Transduction kit
PTM	Heavily O-glycosylated; expresses both type 1 and type 2 core glycans. Heavily N-glycosylated; expresses primarily high mannose and complex bisecting type N-linked glycans. May be phosphorylated. Phosphorylation of the intracellular C-terminal domain may induce proteolytic cleavage and the liberation of the extracellular domain into the extracellular space. May contain numerous disulfide bridges. Association of several molecules of the secreted form may occur through interchain disulfide bridges providing an extraordinarily large gel-like matrix in the extracellular space or in the lumen of secretory ducts.

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