ARG70389
Human MIF recombinant protein (His-tagged, C-ter)
Human MIF recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
Product Description | E. coli expressed, His-tagged (C-ter) Human MIF recombinant protein |
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Tested Application | SDS-PAGE |
Target Name | MIF |
Species | Human |
A.A. Sequence | Met1 - Ala115 |
Expression System | E. coli |
Protein Full Name | Macrophage migration inhibitory factor |
Alternate Names | MIF; Macrophage Migration Inhibitory Factor; GIF; Phenylpyruvate Tautomerase; GLIF; Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor); Glycosylation-Inhibiting Factor; L-Dopachrome Tautomerase; L-Dopachrome Isomerase; MMIF; Epididymis Secretory Sperm Binding Protein; EC 5.3.3.12; EC 5.3.2.1 |
Properties
Form | Powder |
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Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
Purity | >98% (by SDS-PAGE) |
Buffer | PBS (pH 8.0) |
Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Gene Symbol | MIF |
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Gene Full Name | Macrophage Migration Inhibitory Factor |
Background | This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. |
Function | It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. |
Cellular Localization | Cytoplasm, Secreted |
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