ARG82971
Human Lymphotoxin Alpha / TNF beta ELISA Kit
Human Lymphotoxin Alpha / TNF beta ELISA Kit for ELISA and Human
Overview
| Product Description | ARG82971 Human Lymphotoxin Alpha / TNF beta ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Lymphotoxin Alpha / TNF beta in serum, plasma, cell culture supernatant samples. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | Cross-Reactivity: Not reacts with Human GM-CSF, IL8, IL1 beta, TNF alpha and Mouse TNF alpha. |
| Target Name | Lymphotoxin alpha / TNF beta |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 7.8 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 15.6 - 1000 pg/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | LTA; Lymphotoxin Alpha; TNFSF1; TNFB; LT; Tumor Necrosis Factor Ligand Superfamily Member 1; Lymphotoxin-Alpha; LT-Alpha; TNF-Beta; Lymphotoxin Alpha (TNF Superfamily, Member 1); Tumor Necrosis Factor Ligand 1E; Tumor Necrosis Factor Beta; TNF Superfamily, Member 1; TNF Superfamily Member 1; TNLG1E |
Application Instructions
| Assay Time | ~ 4 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LTA |
| Gene Full Name | lymphotoxin alpha |
| Background | The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012] |
| Function | Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. [UniProt] |
| Highlight | Related products: Lymphotoxin alpha antibodies; Lymphotoxin alpha ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
