ARG70060
Human IL17B recombinant protein (Active) (His-tagged, C-ter)
Human IL17B recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Active Human IL17B recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | IL17B |
| Species | Human |
| A.A. Sequence | Gln21 - Phe180 |
| Expression System | E. coli |
| Activity | Active |
| Activity Note | Determined by its ability to induce IL-8 secretion in human PBMCs. The ED50 for this effect is <49 ng/mL. |
| Alternate Names | IL-17B; Interleukin-20; Interleukin-17B; IL-20; Neuronal interleukin-17-related factor; NIRF; Cytokine Zcyto7; ZCYTO7 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >98% (by SDS-PAGE) |
| Buffer | PBS (pH 8.0) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | IL17B |
|---|---|
| Gene Full Name | interleukin 17B |
| Background | The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. [provided by RefSeq, Jul 2008] |
| Function | Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
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ARG70060 Human IL17B recombinant protein (Active) (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70060 Human IL17B recombinant protein (Active) (His-tagged, C-ter).
