ARG83309
Human IL10R subunit beta ELISA Kit
Human IL10R subunit beta ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83309 Human IL10R subunit beta ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IL10R subunit beta in Serum, Plasma and Cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | IL10R subunit beta |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 80 pg/ml |
| Detection Range | 156 pg/ml - 10,000 pg/ml |
| Sample Type | Serum, Plasma and Cell culture supernatants |
| Precision | Intra-Assay CV: 5.3% Inter-Assay CV: 7.0% |
| Alternate Names | Cytokine receptor family 2 member 4; CRFB4; IL-10RB; CRF2-4; Interleukin-10 receptor subunit 2; IL-10R2; D21S66; CD antigen CDw210b; IL-10R subunit 2; Interleukin-10 receptor subunit beta; D21S58; Cytokine receptor class-II member 4; CDW210B; IL-10R subunit beta; IL-10 receptor subunit beta |
Application Instructions
| Assay Time | ~ 5 hours |
|---|
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q08334 Human Interleukin-10 receptor subunit beta |
|---|---|
| Gene Symbol | IL10RB |
| Gene Full Name | interleukin 10 receptor, beta |
| Background | The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq, Jul 2008] |
| Function | Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein. [UniProt] |
Images (1) Click the Picture to Zoom In
-
ARG83309 Human IL10R subunit beta ELISA Kit standard curve image
ARG83309 Human IL10R subunit beta ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG83309 Human IL10R subunit beta ELISA Kit User manual |
 Download
|
