ARG83302

Human ICAM4 ELISA Kit

Human ICAM4 ELISA Kit for ELISA and Human

Overview

Product Description ARG83302 Human ICAM4 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human ICAM4 in Serum, Plasma and Cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity There is no detectable cross-reactivity with other relevant proteins.
Target Name ICAM4
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 20 pg/ml
Detection Range 31.2 pg/ml - 2,000 pg/ml
Sample Type Serum, Plasma and Cell culture supernatants
Precision Intra-Assay CV: 6.5%
Inter-Assay CV: 5.5%
Alternate Names ICAM4; Intercellular Adhesion Molecule 4 (Landsteiner-Wiener Blood Group); CD242; LW; Intercellular Adhesion Molecule 4 (LW Blood Group); Landsteiner-Wiener Blood Group Glycoprotein; Intercellular Adhesion Molecule 4; CD242 Antigen; Intercellular Adhesion Molecule 4, Landsteiner-Wiener Blood Group; Landsteiner-Wiener Blood Group Antigen A; Landsteiner-Wiener Blood Group; LW Blood Group Protein; Bloodgroup LW Protein; LW Antigen A; ICAM-4

Application Instructions

Assay Time ~ 5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3386 Human ICAM4

Swiss-port # Q14773 Human Intercellular adhesion molecule 4

Gene Symbol ICAM4
Gene Full Name Intercellular Adhesion Molecule 4 (Landsteiner-Wiener Blood Group)
Background This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins.
Cellular Localization Cell membrane, Membrane, Secreted
PTM Disulfide bond, Glycoprotein

Images (1) Click the Picture to Zoom In

  • ARG83302 Human ICAM4 ELISA Kit standard curve image

    ARG83302 Human ICAM4 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

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