ARG83303
Human HS6ST1 ELISA Kit
Human HS6ST1 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83303 Human HS6ST1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human HS6ST1 in Serum, Plasma and Cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | HS6ST1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 7.5 pg/ml |
| Detection Range | 15.6 pg/ml - 1,000 pg/ml |
| Sample Type | Serum, Plasma and Cell culture supernatants |
| Precision | Intra-Assay CV: 6.2% Inter-Assay CV: 5.6% |
| Alternate Names | HS6ST1; Heparan Sulfate 6-O-Sulfotransferase 1; HS6ST; Heparan-Sulfate 6-O-Sulfotransferase 1; HS6ST-1; Heparan-Sulfate 6-Sulfotransferase; EC 2.8.2.-; EC 2.8.2; HH15 |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O60243 Human Heparan-sulfate 6-O-sulfotransferase 1 |
|---|---|
| Gene Symbol | HS6ST1 |
| Gene Full Name | Heparan Sulfate 6-O-Sulfotransferase 1 |
| Background | The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene. |
| Function | 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid. |
| Cellular Localization | Membrane |
| PTM | Glycoprotein |
Images (1) Click the Picture to Zoom In
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ARG83303 Human HS6ST1 ELISA Kit standard curve image
ARG83303 Human HS6ST1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG83303 Human HS6ST1 ELISA Kit User manual |
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