ARG70149
Human Galectin 7 recombinant protein (Active) (His-tagged, N-ter)
Human Galectin 7 recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
Overview
Product Description | E. coli expressed, His-tagged (N-ter) Active Human Galectin 7 recombinant protein |
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Tested Application | SDS-PAGE |
Target Name | Galectin 7 |
Species | Human |
A.A. Sequence | Ser2 - Phe136 |
Expression System | E. coli |
Activity | Active |
Activity Note | Determinedd by its ability to agglutinate human red blood cells. The ED50 for this effect is <2 μg/mL |
Alternate Names | GAL7; Gal-7; HKL-14; LGALS7A; Galectin-7; p53-induced gene 1 protein; PI7 |
Properties
Form | Powder |
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Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
Purity | >98% (by SDS-PAGE) |
Buffer | PBS (pH 7.4) |
Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Gene Symbol | LGALS7 |
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Gene Full Name | lectin, galactoside-binding, soluble, 7 |
Background | The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008] |
Function | Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. [UniProt] |
Cellular Localization | Cytoplasm. Nucleus. Secreted. Note=May be secreted by a non-classical secretory pathway. [UniProt] |
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