ARG70121

Human FGF14 recombinant protein (Active) (His-tagged, N-ter)

Human FGF14 recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE

Overview

Product Description E. coli expressed, His-tagged (N-ter) Active Human FGF14 recombinant protein
Tested Application SDS-PAGE
Target Name FGF14
Species Human
A.A. Sequence Ala2 - Thr246
Expression System E. coli
Activity Active
Activity Note Determined by its ability to induce 3T3 cells proliferation. The ED50 for this effect is <21 ng/mL.
Alternate Names FHF4; FHF-4; SCA27; Fibroblast growth factor 14; FGF-14; Fibroblast growth factor homologous factor 4

Properties

Form Powder
Purification Note Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test.
Purity >95% (by SDS-PAGE)
Buffer PBS (pH 7.4)
Reconstitution It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
Storage Instruction For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol FGF14
Gene Full Name fibroblast growth factor 14
Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Function Probably involved in nervous system development and function. [UniProt]
Cellular Localization Nucleus. [UniProt]

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  • ARG70121 Human FGF14 recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image

    SDS-PAGE analysis of ARG70121 Human FGF14 recombinant protein (Active) (His-tagged, N-ter).