ARG70121
Human FGF14 recombinant protein (Active) (His-tagged, N-ter)
Human FGF14 recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
Overview
Product Description | E. coli expressed, His-tagged (N-ter) Active Human FGF14 recombinant protein |
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Tested Application | SDS-PAGE |
Target Name | FGF14 |
Species | Human |
A.A. Sequence | Ala2 - Thr246 |
Expression System | E. coli |
Activity | Active |
Activity Note | Determined by its ability to induce 3T3 cells proliferation. The ED50 for this effect is <21 ng/mL. |
Alternate Names | FHF4; FHF-4; SCA27; Fibroblast growth factor 14; FGF-14; Fibroblast growth factor homologous factor 4 |
Properties
Form | Powder |
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Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
Purity | >95% (by SDS-PAGE) |
Buffer | PBS (pH 7.4) |
Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Gene Symbol | FGF14 |
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Gene Full Name | fibroblast growth factor 14 |
Background | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] |
Function | Probably involved in nervous system development and function. [UniProt] |
Cellular Localization | Nucleus. [UniProt] |
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