ARG83274

Human Desmoglein 3 ELISA Kit

Human Desmoglein 3 ELISA Kit for ELISA and Human

Overview

Product Description ARG83274 Human Desmoglein 3 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Desmoglein 3 in Serum, Plasma and Cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity There is no detectable cross-reactivity with other relevant proteins.
Target Name Desmoglein 3
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 13 pg/ml
Detection Range 15.6 pg/ml - 1,000 pg/ml
Sample Type Serum, Plasma and Cell culture supernatants
Precision Intra-Assay CV: 4.2%
Inter-Assay CV: 5.0%
Alternate Names PVA; 130 kDa pemphigus vulgaris antigen; CDHF6; Cadherin family member 6; Desmoglein-3

Application Instructions

Assay Time ~ 5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1830 Human DSG3

Swiss-port # P32926 Human Desmoglein-3

Gene Symbol DSG3
Gene Full Name desmoglein 3
Background Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq, Jul 2008]
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [UniProt]
Cellular Localization Cell surface. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG83274 Human Desmoglein 3 ELISA Kit standard curve image

    ARG83274 Human Desmoglein 3 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG83274 Human Desmoglein 3 ELISA Kit User manual download icon Download