ARG83260
Human Cathepsin A / CTSA ELISA Kit
Human Cathepsin A / CTSA ELISA Kit for ELISA and Human
Overview
Product Description | ARG83260 Human Cathepsin A / CTSA ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Cathepsin A / CTSA in Serum, Plasma and Cell culture supernatants. |
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Tested Reactivity | Hu |
Tested Application | ELISA |
Specificity | There is no detectable cross-reactivity with other relevant proteins. |
Target Name | Cathepsin A / CTSA |
Conjugation | HRP |
Conjugation Note | Substrate: TMB and read at 450 nm. |
Sensitivity | 13 pg/ml |
Detection Range | 312 pg/ml - 20,000 pg/ml |
Sample Type | Serum, Plasma and Cell culture supernatants |
Precision | Intra-Assay CV: 4.4% Inter-Assay CV: 4.8% |
Alternate Names | CTSA; Cathepsin A; Lysosomal Protective Protein; Carboxypeptidase C; PPGB; Carboxypeptidase Y-Like Kininase; Protective Protein Cathepsin A; Lysosomal Carboxypeptidase A; Carboxypeptidase-L; Urinary Kininase; EC 3.4.16.5; Deamidase; PPCA; GSL; Protective Protein For Beta-Galactosidase (Galactosialidosis); Protective Protein For Beta-Galactosidase; Beta-Galactosidase Protective Protein; Beta-Galactosidase 2; Carboxypeptidase L; EC 3.4.16; GLB2; NGB |
Application Instructions
Assay Time | ~ 5 hours |
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Properties
Form | 96 well |
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Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | CTSA |
Gene Full Name | Cathepsin A |
Background | This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis. |
Function | Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins. |
Cellular Localization | Lysosome |
PTM | Disulfide bond, Glycoprotein, Zymogen |
Images (1) Click the Picture to Zoom In
Title | Download Link |
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ARG83260 Human Cathepsin A / CTSA ELISA Kit User manual | Download |