ARG83260

Human Cathepsin A / CTSA ELISA Kit

Human Cathepsin A / CTSA ELISA Kit for ELISA and Human

Overview

Product Description ARG83260 Human Cathepsin A / CTSA ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Cathepsin A / CTSA in Serum, Plasma and Cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity There is no detectable cross-reactivity with other relevant proteins.
Target Name Cathepsin A / CTSA
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 13 pg/ml
Detection Range 312 pg/ml - 20,000 pg/ml
Sample Type Serum, Plasma and Cell culture supernatants
Precision Intra-Assay CV: 4.4%
Inter-Assay CV: 4.8%
Alternate Names CTSA; Cathepsin A; Lysosomal Protective Protein; Carboxypeptidase C; PPGB; Carboxypeptidase Y-Like Kininase; Protective Protein Cathepsin A; Lysosomal Carboxypeptidase A; Carboxypeptidase-L; Urinary Kininase; EC 3.4.16.5; Deamidase; PPCA; GSL; Protective Protein For Beta-Galactosidase (Galactosialidosis); Protective Protein For Beta-Galactosidase; Beta-Galactosidase Protective Protein; Beta-Galactosidase 2; Carboxypeptidase L; EC 3.4.16; GLB2; NGB

Application Instructions

Assay Time ~ 5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5476 Human CTSA

Swiss-port # P10619 Human Lysosomal protective protein

Gene Symbol CTSA
Gene Full Name Cathepsin A
Background This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis.
Function Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
Cellular Localization Lysosome
PTM Disulfide bond, Glycoprotein, Zymogen

Images (1) Click the Picture to Zoom In

  • ARG83260 Human Cathepsin A / CTSA ELISA Kit standard curve image

    ARG83260 Human Cathepsin A / CTSA ELISA Kit results of a typical standard run with optical density reading at 450 nm.

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