ARG83276

Human Calsyntenin 1 ELISA Kit

Human Calsyntenin 1 ELISA Kit for ELISA and Human

Overview

Product Description ARG83276 Human Calsyntenin 1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Calsyntenin 1 in Serum, Plasma and Cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity There is no detectable cross-reactivity with other relevant proteins.
Target Name CLSTN1
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 13 pg/ml
Detection Range 15.6 pg/ml - 1,000 pg/ml
Sample Type Serum, Plasma and Cell culture supernatants
Precision Intra-Assay CV: 6.7%
Inter-Assay CV: 5.5%
Alternate Names CLSTN1; Calsyntenin 1; KIAA0911; CDHR12; CSTN1; Alzheimer-Related Cadherin-Like Protein; Cadherin-Related Family Member 12 ; Non-Classical Cadherin XB31alpha; Alcadein-Alpha; Calsyntenin-1; ALC-ALPHA; XB31alpha; Alcalpha1; Alcalpha2; Alc-Alpha; PIK3CD; CST-1; CS1

Application Instructions

Assay Time ~ 5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 22883 Human CLSTN1

Swiss-port # O94985 Human Calsyntenin-1

Gene Symbol CLSTN1
Gene Full Name Calsyntenin 1
Background This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Function Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane.
Cellular Localization Cell membrane, Cell projection, Endoplasmic reticulum, Golgi apparatus, Membrane, Nucleus, Postsynaptic cell membrane, Synapse
PTM Glycoprotein

Images (1) Click the Picture to Zoom In

  • ARG83276 Human Calsyntenin 1 ELISA Kit standard curve image

    ARG83276 Human Calsyntenin 1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG83276 Human Calsyntenin 1 ELISA Kit User manual download icon Download