ARG83276
Human Calsyntenin 1 ELISA Kit
Human Calsyntenin 1 ELISA Kit for ELISA and Human
Overview
Product Description | ARG83276 Human Calsyntenin 1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Calsyntenin 1 in Serum, Plasma and Cell culture supernatants. |
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Tested Reactivity | Hu |
Tested Application | ELISA |
Specificity | There is no detectable cross-reactivity with other relevant proteins. |
Target Name | Calsyntenin 1 |
Conjugation | HRP |
Conjugation Note | Substrate: TMB and read at 450 nm. |
Sensitivity | 13 pg/ml |
Detection Range | 15.6 pg/ml - 1,000 pg/ml |
Sample Type | Serum, Plasma and Cell culture supernatants |
Precision | Intra-Assay CV: 6.7% Inter-Assay CV: 5.5% |
Alternate Names | CLSTN1; Calsyntenin 1; KIAA0911; CDHR12; CSTN1; Alzheimer-Related Cadherin-Like Protein; Cadherin-Related Family Member 12 ; Non-Classical Cadherin XB31alpha; Alcadein-Alpha; Calsyntenin-1; ALC-ALPHA; XB31alpha; Alcalpha1; Alcalpha2; Alc-Alpha; PIK3CD; CST-1; CS1 |
Application Instructions
Assay Time | ~ 5 hours |
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Properties
Form | 96 well |
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Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | CLSTN1 |
Gene Full Name | Calsyntenin 1 |
Background | This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. |
Function | Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane. |
Cellular Localization | Cell membrane, Cell projection, Endoplasmic reticulum, Golgi apparatus, Membrane, Nucleus, Postsynaptic cell membrane, Synapse |
PTM | Glycoprotein |
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Title | Download Link |
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ARG83276 Human Calsyntenin 1 ELISA Kit User manual | Download |