ARG70424
Human CXCL3 / GRO gamma recombinant protein (Active) (His-tagged, N-ter)
Human CXCL3 / GRO gamma recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (N-ter) Active Human CXCL3 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CXCL3 / GRO gamma |
| Species | Human |
| A.A. Sequence | Ala35 - Asn107 |
| Expression System | E. coli |
| Protein Full Name | C-X-C motif chemokine 3 |
| Activity | Active |
| Activity Note | Determined by its ability to chemoattract BaF3 cells transfected with human CXCR2. The ED50 for this effect is <2 ng/mL |
| Alternate Names | CXCL3; C-X-C Motif Chemokine Ligand 3; SCYB3; CINC-2b; MIP-2b; GROg; GRO3; Macrophage Inflammatory Protein 2-Beta; Chemokine (C-X-C Motif) Ligand 3; Growth-Regulated Protein Gamma |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >98% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CXCL3 |
|---|---|
| Gene Full Name | C-X-C motif chemokine 3 |
| Background | This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. |
| Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. |
| Cellular Localization | Secreted |
| PTM | Disulfide bond |
Images (1) Click the Picture to Zoom In
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ARG70424 Human CXCL3 / GRO gamma recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70424 Human CXCL3 / GRO gamma recombinant protein (Active) (His-tagged, N-ter)
