ARG83263
Human COLEC12 ELISA Kit
Human COLEC12 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83263 Human COLEC12 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human COLEC12 in Serum, Plasma and Cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | COLEC12 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 13 pg/ml |
| Detection Range | 156 pg/ml - 10,000 pg/ml |
| Sample Type | Serum, Plasma and Cell culture supernatants |
| Precision | Intra-Assay CV: 5.0% Inter-Assay CV: 5.9% |
| Alternate Names | COLEC12; Collectin Subfamily Member 12; SCARA4; SRCL; CL-P1; Scavenger Receptor With C-Type Lectin; Nurse Cell Scavenger Receptor 2; Collectin Placenta Protein 1; Collectin-12; HCL-P1; CLP1; NSR2; Scavenger Receptor Class A, Member 4; Scavenger Receptor Class A Member 4; Collectin Sub-Family Member 12 |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | COLEC12 |
| Gene Full Name | Collectin Subfamily Member 12 |
| Background | This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells. |
| Function | Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid-beta in Alzheimer disease. |
| Cellular Localization | Membrane |
| PTM | Disulfide bond, Glycoprotein |
Images (1) Click the Picture to Zoom In
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ARG83263 Human COLEC12 ELISA Kit standard curve image
ARG83263 Human COLEC12 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83263 Human COLEC12 ELISA Kit User manual |
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