ARG83250
Human CFHR1 ELISA Kit
Human CFHR1 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83250 Human CFHR1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CFHR1 in Serum, Plasma and Cell culture supernatants. |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | CFHR1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 25 pg/ml |
| Detection Range | 312 pg/ml - 20,000 pg/ml |
| Sample Type | Serum, Plasma and Cell culture supernatants |
| Precision | Intra-Assay CV: 6.4% Inter-Assay CV: 5.9% |
| Alternate Names | CFHR1; Complement Factor H Related 1; FHR1; CFHL; CFHL1P; CFHR1P; H36-1; H36-2; CFHL1; HFL1; HFL2; Complement Factor H-Related 1 Pseudogene; Complement Factor H-Related Protein 1; H Factor (Complement)-Like 1; H Factor (Complement)-Like 2; H Factor-Like Protein 1; H-Factor-Like 1; FHL-1; FHR-1; H36; Complement Factor H-Related 1 |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q03591 Human Complement factor H-related protein 1 |
|---|---|
| Gene Symbol | CFHR1 |
| Gene Full Name | Complement Factor H Related 1 |
| Background | This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. |
| Function | Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. |
| Cellular Localization | Secreted |
| PTM | Disulfide bond, Glycoprotein |
Images (1) Click the Picture to Zoom In
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ARG83250 Human CFHR1 ELISA Kit standard curve image
ARG83250 Human CFHR1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83250 Human CFHR1 ELISA Kit User manual |
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