ARG70455
Human CDNF recombinant protein (His-tagged, C-ter)
Human CDNF recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Human CDNF recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CDNF |
| Species | Human |
| A.A. Sequence | Gln27 - Leu187 |
| Expression System | E. coli |
| Protein Full Name | Cerebral dopamine neurotrophic factor |
| Alternate Names | CDNF; Cerebral Dopamine Neurotrophic Factor; Conserved Dopamine Neurotrophic Factor; ARMETL1; Arginine-Rich, Mutated In Early Stage Tumors-Like 1; ARMET-Like Protein 1 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >98% (by SDS-PAGE) |
| Buffer | PBS (pH 8.0) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CDNF |
|---|---|
| Gene Full Name | Cerebral Dopamine Neurotrophic Factor |
| Background | Predicted to enable growth factor activity. Predicted to be involved in dopaminergic neuron differentiation and neuron projection development. Predicted to be active in endoplasmic reticulum and extracellular space. |
| Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). |
| Cellular Localization | Secreted |
| PTM | Disulfide bond |
Images (1) Click the Picture to Zoom In
-
ARG70455 Human CDNF recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70455 Human CDNF recombinant protein (His-tagged, C-ter)
