ARG81331
Human CD261 / TRAIL-R1 ELISA Kit
Human CD261 / TRAIL-R1 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG81331 Human CD261 / TRAIL-R1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD261 / TRAIL-R1 in serum, plasma and cell culture supernatant. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | Specific for Human CD261 / TRAIL-R1. No cross reactivity observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R2, TRAIL R3, TRAIL R4, CD178 and Granzyme B. |
| Target Name | CD261 / TRAIL R1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 8 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 31.25 - 1000 pg/ml |
| Sample Volume | 100 µl |
| Alternate Names | TNF-related apoptosis-inducing ligand receptor 1; CD antigen CD261; TRAILR-1; DR4; Tumor necrosis factor receptor superfamily member 10A; CD261; Death receptor 4; APO2; TRAIL receptor 1; TRAIL-R1; TRAILR1 |
Application Instructions
| Assay Time | ~ 2.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O00220 Human Tumor necrosis factor receptor superfamily member 10A |
|---|---|
| Gene Symbol | TNFRSF10A |
| Gene Full Name | tumor necrosis factor receptor superfamily, member 10a |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008] |
| Function | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. [UniProt] |
| Highlight | Related products: CD261 antibodies; CD261 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
Images (1) Click the Picture to Zoom In
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ARG81331 Human CD261 / TRAIL-R1 ELISA Kit standard curve image
ARG81331 Human CD261 / TRAIL-R1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG81331 Human CD261 / TRAIL-R1 ELISA Kit User's manual |
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