ARG83246

Human CD226 ELISA Kit

Human CD226 ELISA Kit for ELISA and Human

Overview

Product Description ARG83246 Human CD226 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD226 in Serum, Plasma and Cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity There is no detectable cross-reactivity with other relevant proteins.
Target Name CD226
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 7 pg/ml
Detection Range 93.7 pg/ml - 6,000 pg/ml
Sample Type Serum, Plasma and Cell culture supernatants
Precision Intra-Assay CV: 6.0%
Inter-Assay CV: 6.9%
Alternate Names TLiSA1; CD antigen CD226; PTA1; CD226 antigen; DNAM-1; DNAX accessory molecule 1; DNAM1

Application Instructions

Assay Time ~ 5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10666 Human CD226

Swiss-port # Q15762 Human CD226 antigen

Gene Symbol CD226
Gene Full Name CD226 molecule
Background This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Function Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705). [UniProt]
Cellular Localization Cell membrane; Single-pass type I membrane protein. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG83246 Human CD226 ELISA Kit standard curve image

    ARG83246 Human CD226 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG83246 Human CD226 ELISA Kit User manual download icon Download