ARG83311
Human CD125 / IL5RA ELISA Kit
Human CD125 / IL5RA ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83311 Human CD125 / IL5RA ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD125 / IL5RA in Serum, Plasma and Cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | CD125 / IL5RA |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 17 pg/ml |
| Detection Range | 31.2 pg/ml - 2,000 pg/ml |
| Sample Type | Serum, Plasma and Cell culture supernatants |
| Precision | Intra-Assay CV: 4.0% Inter-Assay CV: 5.2% |
| Alternate Names | CD125; CDw125; IL-5 receptor subunit alpha; IL5R; Interleukin-5 receptor subunit alpha; CD antigen CD125; HSIL5R3; IL-5R-alpha; IL-5R subunit alpha; IL-5RA |
Application Instructions
| Assay Time | ~ 5 hours |
|---|
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q01344 Human Interleukin-5 receptor subunit alpha |
|---|---|
| Gene Symbol | IL5RA |
| Gene Full Name | interleukin 5 receptor, alpha |
| Background | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011] |
| Function | This is the receptor for interleukin-5. The alpha chain binds to IL5. [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG83311 Human CD49e / Integrin alpha 5 ELISA KitHuman CD125 / Human CD125 / IL5RA ELISA Kit standard curve image
ARG83311 Human CD49e / Integrin alpha 5 ELISA KitHuman CD125 / Human CD125 / IL5RA ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG83311 Human CD49e / Integrin alpha 5 ELISA KitHuman CD125 / Human CD125 / IL5RA ELISA Kit User manual |
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